The The Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) core uses analytical chemistry and pharmacologic infrastructure to supports the translational development of drugs, anticancer agents, and carrier-mediated agents.  The lab provides bioanalytical services including LC-MS assay development, validation and analysis of samples to quantify a wide variety of drugs, ranging from small molecule therapeutics to complex drugs such as monoclonal antibodies, drug conjugates and polymers.  The ATPAC is equipped to support your entire project:  assistance in PK/PD study design, LC-MS/MS or ICP-MS assay development, quantification of drugs from biological samples, PK/PD analysis and report generation. Website

The Biomarker Mass Spectrometry Core in the Gillings School of Global Public Health has expertise in qualitative and quantitative analysis of a variety of low molecular weight biomarkers of exposure and effect. Examples of some of the analytes we measure include environmental toxicants, DNA adducts, short chain fatty acids, metabolites, amino acids and short peptides, and metals. We work with diverse sample matrices including drinking water, plant extracts, in vitro cell lysates, biological fluids and tissue extracts. Our facility is open to all UNC researchers, and we offer full service analysis, new method development, and training for independent operation of our instrumentation. Website

Welcome to the UNC School of Pharmacy Clinical Pharmacology and Analytical Chemistry Laboratory web site! Our faculty and staff facilitate research in preclinical and clinical pharmacology and analytical chemistry in pursuit of a common goal: optimizing the prevention and treatment of HIV infection. We invite you to learn more about our vigorous research agenda. You are welcome to contact us for further information on our activities and services. We also encourage you to visit the UNC Center for AIDS Research website and our Clinical Pharmacology and Analytical Chemistry Core website. Website

The Department of Chemistry Mass Spectrometry Laboratory specializes in small molecule MS analysis. Our suite of instrumentation is capable of accurate mass determination for both volatile and non-volatile speciation. In addition, we provide high quality inline liquid chromatographic separations coupled with and without photodiode array detection (PDA). Our lab is well versed in small molecule characterization, fragmentation, and quantitation. Our client’s research span a wide range of applications from plant phytohormones to photoredox catalyzed reaction meachanisms to drug interaction studies. Our services can be tailored to meet the most demanding analytical experiments. The lab offers Individualized user training for undergraduate, graduate, & post-doctoral scholars. Website

The Proteomics Core Facility in the UNC School of Medicine offers mass spectrometry-based proteomics services to identify and quantify proteins on systems-wide or targeted level. From this, a protein’s post-translational modifications, protein-protein interactions and global changes in the proteome or phosphoproteome can be measured. The Center offers an array of sample preparation and instrumentation services, as well as method development and in-depth consultation. Our staff will also assist with statistical and bioinformatics analysis so that researchers can get the most out of their data. Website